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MILLS, GORDON B

One or more keywords matched the following items that are connected to MILLS, GORDON B

Item Type	Name
Academic Article	High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.
Concept	MAP Kinase Kinase 7
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	MAP Kinase Kinase 3
Concept	MAP Kinase Kinase Kinases
Concept	MAP Kinase Kinase 4
Concept	MAP Kinase Kinase 1
Academic Article	Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer.
Academic Article	Cetuximab attenuates metastasis and u-PAR expression in non-small cell lung cancer: u-PAR and E-cadherin are novel biomarkers of cetuximab sensitivity.
Academic Article	Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance.
Academic Article	Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.
Academic Article	The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28.
Academic Article	Sustained activation of JNK/p38 MAPK pathways in response to cisplatin leads to Fas ligand induction and cell death in ovarian carcinoma cells.
Academic Article	Evidence that phosphatidylinositol 3-kinase- and mitogen-activated protein kinase kinase-4/c-Jun NH2-terminal kinase-dependent Pathways cooperate to maintain lung cancer cell survival.
Academic Article	Structure-activity relationships of fluorinated lysophosphatidic acid analogues.
Academic Article	Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells.
Academic Article	Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity.
Academic Article	Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition.
Academic Article	Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers.
Academic Article	PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas.
Academic Article	Co-targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor-resistant melanoma.
Academic Article	Autotaxin exacerbates tumor progression by enhancing MEK1 and overriding the function of miR-489-3p.
Academic Article	Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells.
Academic Article	Defective Replication Stress Response Is Inherently Linked to the Cancer Stem Cell Phenotype.
Academic Article	Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study.
Academic Article	MEK Inhibition Remodels the Immune Landscape of Mutant KRAS Tumors to Overcome Resistance to PARP and Immune Checkpoint Inhibitors.
Academic Article	TOP1 modulation during melanoma progression and in adaptative resistance to BRAF and MEK inhibitors.

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Mitogen Activated Protein Kinase Kinases